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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Descript 28% of U. S. adults

C.

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its performance. This can increase side effects, such as headaches or dizziness, while prolonging the absorption of tadalafil in the gastrointestinal tract. Do not take Cialis in non-food contexts, such as drinks, fat, or meal blocker formi cation; while using this medication, avoid alcohol, grapefruit, or grapefruit juice.

Do not crush, split, or chew (QT interval), if you are taking Cialis or switching to an alpha-blocker to reduce its blood pressure. The medications Tadalafil and Sildenafil can interact with.

Do not take Cialis (tadalafil) with:

  • Acidifying agentsused to treat heartburn or ulcers: Tadalafil can cause fluid loss and/or kidney dysfunction, indigestion, or heartburn when taken with Cialis.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Standard Interactions:
Medicationysb-interactions
Cialis (tadalafil)30mg
60mg
90mg
130mg
.25mg
.5mg
1mg

Cialis: A Comprehensive Guide to Its Uses, Benefits, and Side Effects Introduction: Tadalafil, commonly known as Cialis, is a medication commonly used to treat erectile dysfunction (ED) in men. It belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors, which work by increasing blood flow to the penis during sexual stimulation. This article aims to provide a comprehensive understanding of tadalafil's uses, benefits, side effects, and precautions associated with its use in men. What is Tadalafil Used for? Tadalafil belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It works by increasing blood flow to the penis, enabling a man to achieve and maintain an erection. While it's not approved for use in women, it's typically prescribed for men who have erectile dysfunction. What Are the Uses of Tadalafil in Men? Tadalafil is primarily used to treat erectile dysfunction (ED) in men. It is also used to treat pulmonary arterial hypertension (PAH) and benign prostatic hypertrophy (BPH). How Does Tadalafil Work? Tadalafil belongs to a class of drugs known as PDE5 inhibitors. It works by inhibiting the enzyme PDE5, which is responsible for breaking down cyclic guanosine monophosphate (cGMP) into two phosphodiesterase type 5 (PDE5) enzymes. By doing so, it promotes increased levels of cGMP in the body, which helps to relax the muscles in the penis and improve blood flow. How to Take Tadalafil? Tadalafil is typically taken orally, with or without food, approximately 30 to 60 minutes before sexual activity. It's important to follow the dosing instructions provided by your healthcare provider, including the recommended dosage and duration of use. What Precautions Should I Take When Taking Tadalafil? Tadalafil is generally taken once a day, with or without food, approximately 30 minutes to 1 hour before sexual activity. It's important to take it with a full glass of water, as this may decrease the effectiveness of the medication. How to Use Tadalafil? Tadalafil should be taken as directed by a healthcare professional, and is typically taken orally, with or without food, approximately 30 minutes to 1 hour before sexual activity. How Long Does Tadalafil Last? Tadalafil can remain effective for up to 36 hours, allowing for a sustained erection for up to 5 hours. Before taking Tadalafil, it's important to discuss all of your medical history, including any medications you're currently taking, any allergies you're currently having, and any other medications you're currently taking. Can I Drink Alcohol While Taking Tadalafil? There are a few precautions to take while taking tadalafil. While taking tadalafil, it's important to avoid any alcoholic beverages, which can increase the risk of side effects. Additionally, tadalafil can interact with other medications, so it's always recommended to consult with your healthcare provider before starting any new medication, including tadalafil. How to Store Tadalafil? Tadalafil should be kept in a cool, dry place, away from direct sunlight and moisture. You should store it in a cool, dark place, away from direct sunlight and moisture. Where Can I Buy Tadalafil Online? Purchasing tadalafil from reputable sources requires careful consideration and vigilance. Online pharmacies may sell counterfeit or ineffective medications, potentially rendering them ineffective or even harmful. Always follow your healthcare provider's instructions for safe and effective use of tadalafil.

Tadalafil and Cialis are two of the most common prescription medicines for treating ED. They are also known as PDE5 inhibitors, and Cialis is the generic name for this medicine. Cialis works by relaxing muscles and widening the blood vessels in the penis. Cialis does not work on the same basis as Viagra, but it has been approved by the FDA to treat ED in both males and females. However, it does not work on all men. Cialis has been approved by the FDA since 2003, and Cialis is a prescription medicine. There are only a few side effects of Cialis, and they have been listed below. Tell your doctor if you have any of the following side effects of Cialis: headache, stomach pain, back pain, muscle pain, nasal congestion, and vision changes, dizziness, or changes in vision. If you are taking any of the following medications, tell your doctor about it. These medications are known as PDE5 inhibitors. They work by relaxing muscles and widening the blood vessels in the penis. They also increase blood flow to your penis. Cialis is a selective PDE5 inhibitor. It works on the same mechanism as Viagra, but it does not work on all men. Cialis is also known as the generic name for the other PDE5 inhibitor, but it is not available on the generic name. Some people may have some side effects of Cialis, while others may not have any side effects. Tell your doctor if you have any questions about Cialis.

VIDEO

Cialis and other PDE5 inhibitors are also known as PDE5 inhibitors, which means that they work by increasing the amount of the chemical in the body that is needed to control a disease. They are also known as Cialis. Cialis is a brand name for tadalafil, and it is not available in Australia as Cialis.